Your doctor may ask you to start taking the drug either on day 3 or day 5 of your menstrual cycle. If you have more questions about how Femara and clomiphene are alike and different, talk with your doctor. Letrozole works by decreasing the amounts of these hormones in the body. The Food and Drug Administration (FDA) approves prescription drugs such as Femara to treat certain conditions. You can also visit the Femara manufacturers website to see if there are support options. How to Reduce Your Risk of Breast Cancer: 10 Lifestyle Recommendations, Symptoms of Late Stage Metastatic Breast Cancer, What to Know and Consider Before Having Prophylactic Mastectomy. Femara is also used off-label to treat infertility. * Risk factors for osteoporosis include a family history of the condition, low physical activity, smoking, drinking alcohol, and a diet low in calcium and vitamin D. It should be safe to drink alcohol during your Femara treatment. Heres some detail on several of the side effects this drug cause. You should always consult your doctor or another healthcare professional before taking any medication. Breast cancer develops when cells in your breast tissue start to grow and multiply more quickly than usual. You should not stop taking Letrozole without discussing with your physician. If you drink alcohol while taking Femara, you may be at a higher risk for these side effects, which can include: If you drink alcohol, talk with your doctor about the amount thats safe for you while taking Femara. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Your side effect notes can include things such as: Keeping notes and sharing them with your doctor will help them learn more about how the drug affects you. You should always consult your doctor or another healthcare professional before taking any medication. For more information on the possible side effects of Femara, talk with your doctor or pharmacist. How does Arimidex work? Based on when your period begins, your doctor will advise you when to start treatment. Femara will start working soon after you start taking it. Studies conducted by maxillofacial surgeons have shown that most of the free-flowing chemical in the bloodstream is eliminated in approximately three to four months. Most people will take Femara to treat their breast cancer for at least 5 years. Both cancer and cancer treatments can often cause changes in appetite and body weight. If your doctor gives you the OK, here's a gentle routine to try. If you develop serious side effects while taking Femara, call your doctor right away. If you miss a dose, do not take a double dose the next day. Off-label use is when a drug thats approved to treat one condition is used to treat another condition. Its used to treat the following types of cancer: Femara comes as a tablet you take by mouth once per day. It may also be used when someone is premenopausal and having treatment to stop the ovaries working (temporary menopause). If youre concerned about side effects from stopping Femara treatment after 5 years, talk with your doctor. vaginal spotting. 1 Some fertility experts recommend taking the pills on days 3, 4, 5, 6, and 7 of your cycle. Most people are given letrozole for 5 years, but some will take it for up to 10 years. Femara may cause reduced bone mineral density (weakened bones) in some people. The drug works by lowering estrogen levels in your body, which helps stop breast cancer from growing. If you find the side effects ease within the two weeks they may try you on Anastrozole or even Exemstane. But the drug could be harmful to a child who consumes it in breast milk. If you experience side effects that dont go way or interfere with your daily life, talk with your doctor or pharmacist. Letrozole is a pill, taken by mouth. And your doctor can use this information to adjust your treatment plan if needed. * For more information about this side effect, see the "Side effect focus" section below. Many drugs are available to treat infertility. For this use, youll usually take the drug for 5 years following surgery to remove the cancer. How long side effects last can vary from person to person. Femara isnt currently approved to treat infertility in females. Your doctor will determine the best dosage to fit your needs. This means that your doctor and insurance company will need to communicate about your prescription before the insurance company will cover the drug. Using this medicine while you are pregnant can harm your unborn baby. Read on to learn how to take Femara, what its uses and side effects are, and more. When you take the drug, it stops androgens in your body from converting into estrogen. The most common cause of ovulation problems that result in infertility is polycystic ovary syndrome (PCOS). But Femara is also sometimes used to treat infertility that doesnt have an obvious cause. And they want you to get the best care possible. Learn about the dosage for Femara in treating certain types of breast cancer. You can take your dose at any time of the day. Note: The Food and Drug Administration (FDA) tracks side effects of drugs they have approved. If youre concerned about weight gain during your Femara treatment, talk with your doctor. Here are a few other questions you may want to ask your doctor about Femara: In addition, you can learn about breast cancer and its treatment options by subscribing to Healthlines breast cancer newsletter. Severe liver problems can cause the level of Femara to build up in your body, which can raise your risk for side effects. Factors to consider include those in the list below. Letrozole can stop or slow the growth of these cancers. Limiting alcohol, caffeine, and spicy foods. This helps stop breast cancer from growing. If you dont understand something related to your condition or treatment, ask your doctor to explain it to you. Your doctor will explain how you should take Femara, such as how much to take and how often. Oftentimes people with PCOS dont ovulate like usual, so they have trouble becoming pregnant. Femara is meant to be used as a long-term treatment for breast cancer. Avoid storing this medication in areas where it could get damp or wet, such as in bathrooms. These hormones stimulate an egg in your ovary to mature and be released from your ovary. If you think you could be pregnant or have pregnancy symptoms, tell your doctor before you start taking Femara. Medically reviewed by Carmen Fookes, BPharm. This may happen more often if used for a long time. Keep in mind that side effects of a drug can depend on: Your doctor or pharmacist can tell you more about the potential side effects of Femara. Hot flashes. For instance, some interactions can interfere with how well a drug works. For some people, Femara may cause fatigue or dizziness. Your bones rely on estrogen to keep them strong. If youre breastfeeding, talk with your doctor before you start taking Femara. If you have questions about using Femara, talk with your doctor. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Chemotherapy is a type of cancer drug. If you have fatigue or dizziness while youre taking Femara, dont drive or operate other machines. Prophylactic mastectomy is surgery to remove breast tissue. Be sure to always take Femara exactly as your doctor recommends. But if you have any symptoms that are ongoing or that bother you, talk with your doctor or pharmacist. If you have questions or concerns about changes in your weight, talk with your doctor or pharmacist. Whether Femara or clomiphene is more effective for you may depend on the cause of your infertility. And some may be easily managed, too. For these women, infertility may be caused by problems with ovulation, or it may not have an obvious cause (called unexplained infertility). Liver problems. This can make your bones weaker and easier to break. The usual dosage of Femara for adjuvant treatment of breast cancer is one tablet taken by mouth once each day. Femara can stay in your system for several weeks after your last dose. swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your mouth, tongue, or throat, which can make it hard to breathe, what dosage of the drug you were taking when you had the side effect, how soon after starting that dosage you experienced it, any other medications you were also taking, any other information you feel is important. Femara is FDA-approved to treat advanced breast cancer thats hormone receptor-positive (HR+). By stopping aromatase from working, Femara lowers the amount of estrogen in your body. * An allergic reaction is possible after taking Femara. Talk with your doctor about your health history before you take Femara. Its a type of drug called an aromatase inhibitor. headache*. Symptoms of a mild allergic reaction can include: A more severe allergic reaction is rare but possible. So, side effects that you have while taking Femara may continue for a few weeks after you stop using it. * For more information about using Femara for infertility, see the section Off-label use of Femara for infertility above. How do Femaras side effects compare with those of other cancer drugs? They can recommend some ways to manage this side effect. Learn the signs and symptoms of metastasis, how you can make yourself as comfortable as possible, and tips for managing end-of-life symptoms. If you have questions or concerns about using Femara for infertility, talk with your doctor. In other words, it takes about 2 days for your body to get rid of half of a Femara dose. This increases your risk of breaking a bone during Femara treatment. No, Femara tablets should be swallowed whole. Below youll find answers to some frequently asked questions about Femaras side effects. Femara contains the active drug letrozole and is available as a generic drug called letrozole. This stops estrogen from being able to stimulate breast cancer cells to grow and multiply. Femara is a hormone therapy thats approved to treat certain forms of breast cancer in females* whove gone through menopause. What can I do to help relieve this side effect? Its also worth noting that alcohol is known to increase the risk of developing breast cancer. If you have questions about any symptoms after stopping Femara, talk with your doctor. Examples of both mild and serious side effects that can occur when using Femara for infertility include: Youll usually take Femara by mouth once daily for 5 days after the start of your menstrual cycle. For this use, youll take Femara for a few days after the start of your period. Femara can cause mild or serious side effects. Femara is used in the following ways to treat advanced breast cancer: Femara has been found to be effective in treating advanced breast cancer. How long a medication remains good can depend on many factors, including how and where you store the medication. What are some frequently asked questions about Femara? Oestrogen stimulates some breast cancers to grow. If youre not having periods when starting Femara, your doctor will recommend when you should start taking the drug. Learn more about some of the side effects that Femara may cause. The mild side effects of Femara that are more common* can include: The mild side effects of Femara that are less common** can include: * Occurred in more than 20% of people in clinical studies ** Occurred in 20% or less of people in clinical studies. Common side effects can be like menopause symptomsand include hot flushes, difficulty sleeping, tiredness and low mood. Swelling, another common side effect of Femara, can cause you to gain weight as your body holds on to water. You may also gain weight if you have swelling, which is another possible side effect of Femara. If you have questions about how Femara may affect your bone density, talk with your doctor. Femara can interact with several types of drugs. Allergic reaction. Femara and clomiphene are both used to induce (cause) ovulation in females* who are having trouble becoming pregnant. After menopause, your body produces less estrogen, which can weaken your bones. Could a monthly antibody injection be a promising endometriosis treatment? (Day 1 of your menstrual cycle is the first day of your period.) Femara is classified as an aromatase inhibitor. Blood tests may be needed to check for unwanted effects. These include: The following information describes dosages that are commonly used or recommended. Swelling from Femara usually occurs in your arms, feet, hands, or legs. Most side effects of Femara are mild. * Sex and gender exist on spectrums. The drugs work by lowering estrogen levels in your body, which helps stop breast cancer from growing. Spotting may occur with Femara use. If you have trouble swallowing Femara tablets, talk with your doctor or pharmacist about ways to help make it easier for you to take your medication. * However, its sometimes used off-label for this use. How many cycles of letrozole are needed to get pregnant? You can also call 800-222-1222 to reach the American Association of Poison Control Centers, or use its online resource. Before taking Femara, be sure to tell your doctor about all medications you take, including prescription and over-the-counter types. Letrozole is usually taken for 5 years, but may be recommended for up to 10 years depending on individual circumstances. This may raise the chance of broken bones. If you experience fatigue during your Femara treatment that doesnt go away or thats bothersome, talk with your doctor. This product is available in the following dosage forms: Tablet It should be safe to drink alcohol during your Femara treatment. Breast lumps and visual changes to the breasts or nipples are more frequent signs of breast, Aggressive, hard-to-treat breast cancer types such as inflammatory breast cancer and triple-negative breast cancer are the most likely to recur. PCOS is a condition that causes hormone problems, irregular or skipped periods, and cysts on your ovaries. In fact, aromatase inhibitors such as Femara are recommended in current guidelines for people with HR+ breast cancer. It is very important that your doctor check your progress at regular visits to make sure that this medicine is working properly. The FDA website provides several useful tips on medication disposal. Weight gain. Femara is also sometimes used off-label to treat infertility in females with endometriosis. They may be able to suggest ways to help manage this side effect. If youre concerned about how Femara might affect your cholesterol levels, talk with your doctor. Is the ketogenic diet right for autoimmune conditions? When is the best time of day to take letrozole? In addition, a small study found that Femara may be effective in treating infertility in men who have both obesity and low testosterone levels. This enzyme is the main way that your body makes estrogen after youve gone through menopause. The usual dosage of Femara for breast cancer treatment is one tablet taken by mouth once each day. If you drink alcohol and youre concerned about how this might affect your condition, talk with your doctor. November 24, 2017. You can also talk with your doctor or pharmacist to learn more. Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. What could happen if I become pregnant during my Femara treatment? Taking letrozole for long periods of time has been associated with an increased risk of bone fractures and heart side effects. If you miss a dose of Femara, take it as soon as you remember, unless its almost time for your next dose. Female hormones that occur naturally in the body can increase the growth of some breast cancers. You might take a look at the Calling Long Term Survivors thread, I believe there's a couple of women who have been on it for 4+ years. We comply with the HONcode standard for trustworthy health information. Before your appointment, write down questions such as: How will Femara affect my body, mood, or lifestyle? So, side effects that you have while taking Femara may continue for a few weeks after you stop using it. (With dependence, your body needs the drug in order to function like usual.) How Viagra became a new 'tool' for young men, Ankylosing Spondylitis Pain: Fact or Fiction, Zara Risoldi Cochrane, Pharm.D., M.S., FASCP, Common sweetener erythritol tied to higher risk of stroke and heart attack, Gout: How metabolic syndrome may increase the risk, A new therapeutic target for the prevention of heart failure due to aortic stenosis, Skipping breakfast and fasting may compromise the immune system. As with most drugs, some people can have an allergic reaction after taking Femara. These symptoms could be life threatening and require immediate medical care. Femara is used off-label to treat infertility in females. Those that have been reported with Femara include: To learn more about each of these side effects, see Side effects explained below. Keeping cool with a fan or removing layers of clothing during hot flash episodes. Stopping Femara isnt known to cause any withdrawal symptoms. A 2019 review of studies also found Femara to be more effective than clomiphene in treating infertility in females* with PCOS. Letrozole lowers the levels of the female sex hormone oestrogen in the body. Different interactions can cause different effects. Learn. Note: After the Food and Drug Administration (FDA) approves a drug, it tracks side effects of the medication. Femara is used off-label for this purpose. They work by lowering estrogen levels within your body, which helps stop the growth of breast cancer. Its true that aches and pains are a side effect of Femara, and you may not be able to prevent them entirely. What are the different types of breast cancer surgery? And the drug doesnt need to be stopped gradually to prevent side effects from occurring. When will I ovulate after taking letrozole? In certain situations, if Femara has stopped working for you, your doctor might ask you to stop taking the drug in order to cause a withdrawal response. This response is a hormonal shift thats caused by stopping Femara. Side effects usually improve after a few months as your body gets used to the medicine. Most of these side effects may go away within a few days or a couple of weeks. improved overall survival. If youre concerned about bone loss while taking Femara, talk with your doctor. Femara may cause fatigue (lack of energy) in some people. Femara can decrease bone mineral density in some people. High cholesterol. Also tell them about any vitamins, herbs, and supplements you use. This article explains how the foods you eat affect your estrogen levels and covers what dietary patterns are associated with elevated, as well as, Researchers say radiation treatments for breast cancer in women over the age of 65 do not appear to affect the rate of survival, The former Dancing with the Stars host shares how becoming her own advocate saved her life and why she's passionate about sharing the benefits of, New research suggests that melatonin may help lower the risk of breast cancer, slow the growth of breast cancer, and help make breast cancer. Off-label drug use is when a drug thats approved for one use is used for a different one thats not approved. To find out how effective Femara was for infertility in clinical studies, see the drugs prescribing information. Before taking Femara, talk with your doctor about your health history. This use of the drug is called ovulation induction. (Day 1 of your menstrual cycle is the first of your period.) Can Breast Cancer Be Detected in a Complete Blood Count (CBC)? Certain drugs, such as paroxetine (Brisdelle, Paxil), are used to treat hot flashes. My doctor said Femara may cause hot flashes. When you get Femara from the pharmacy, the pharmacist will add an expiration date to the label on the bottle. Pet and bone scans show no metastatic activity (again, so far) so fingers crossed it keeps working. Prophylactic mastectomy is surgery to remove breast tissue. Learn how CBCs are used in the treatment of breast cancer. But this side effect wasnt reported in studies. One 2011 study looked at using doses higher than the current standard dose to treat infertility. Lymph node surgery helps doctors determine, Knowing the early signs of breast cancer can help a person seek prompt treatment and improve their chance of survival. 2005-2023 Healthline Media a Red Ventures Company. But sometimes the drug is used off-label in people with this condition. They can help determine if you should keep taking Femara or switch to a different treatment. Mild side effects of Femara can usually go away within a few days or a couple weeks. Use an effective form of birth control to keep from getting pregnant during . You shouldnt use Femara while pregnant or breastfeeding. If youre concerned about hair loss while taking Femara, talk with your doctor. Its possible that any side effect of Femara may last throughout your treatment. The generic is considered to be as safe and effective as the original drug. They can also suggest ways to help reduce side effects. This is because drinking a lot of alcohol can increase your risk of osteoporosis, which is already increased by the drug. . If you experienced side effects while taking Femara, those side effects may not go away for a few weeks after your last dose. They both do the same job but Anastrozole is the more similar tablet so could well have similar side effects - You could ask about the Exemestane which I think are steroid based ? However, the drug may be used off-label for this purpose. If you have breast cancer, you may be wondering if it's safe to practice yoga. Below are brief descriptions of each type of breast cancer Femara is used to treat: Before taking Femara, its important to talk with your doctor about your overall health and other medical conditions you have. If you and your doctor determine that Femara is safe and effective for you, youll likely take it long term. Breast cancers that are stimulated by hormones, such as estrogen, are called hormone receptor-positive (HR+). Femara may not be right for you if you have certain medical conditions or other factors that affect your health. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Femara comes as 2.5-mg tablets that are taken by mouth. Using more than this can lead to serious side effects. Stopping Femara treatment isnt known to cause side effects. Both Femara and Arimidex belong to a group of drugs called aromatase inhibitors. You should keep taking Femara for as long as your doctor recommends. But studies comparing the two drugs have found slightly differing results. Tell them about all prescription, over-the-counter, and other drugs you take. Serious side effects from Femara can occur, but they arent common. As a type of hormone therapy, Femara works by lowering estrogen levels in your body. Risks of extended treatment to consider may include weakening of your bones or raised cholesterol levels. Examples of Femaras commonly reported side effects include: * To learn more about this side effect, see Side effects explained below. To help make sure that you dont miss a dose, try setting a reminder on your phone. Not taking letrozole for the recommended time may increase the risk of your breast cancer coming back. (With osteoporosis, you have weak, thin bones.). Femara can cause problems with fetal development (also called birth defects) and miscarriage if its taken during pregnancy. There's no way to completely predict or prevent breast cancer. Generally it takes four to five half-lives for a drug to be eliminated from the body, so in the case of Arimidex this would be 150 to 300 hours, or six to 12 days. This was common in clinical studies of the drug. This dosage is 1 tablet once daily. If youd like to know more about how Femara and Arimidex compare with each other, see this detailed breakdown. Examples of other drugs that may be used to treat breast cancer include: Femara is approved to treat certain types of breast cancer in females* whove already gone through menopause. You should also talk with them if youre breastfeeding or considering breastfeeding. One example of an androgen is the hormone testosterone. It also helps keep the drug from harming the environment. When used for this purpose, Femara helps lower the risk of your cancer coming back. But its not known if drinking alcohol after youre diagnosed with breast cancer can make your cancer worse or more likely to come back after treatment. However, there are steps you can take to reduce your risk. Although theyre not common side effects, in some cases, Femara can cause anxiety or depression. Some people may have an allergic reaction to Femara. You may also be able to ease headaches by applying an ice pack or heating pad to your head. If you have symptoms of a severe allergic reaction, such as swelling or trouble breathing, call 911 or your local emergency number right away. With advanced breast cancer, the cancer has spread to nearby areas or lymph nodes (called locally advanced breast cancer), or it has spread to other parts of the body (called metastatic breast cancer). Another 2019 review of studies found Femara and clomiphene to be similarly effective in treating unexplained infertility. At that point, the aromatase enzyme is the main pathway that your body uses to make estrogen. For this purpose, Femara is usually used to help lower the risk of the cancer coming back after its been removed by surgery. A hot shower or bath may also provide some headache relief. The lists below describe some of the more common side effects that Femara may cause. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. 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